Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.15066566 Released 2025-03-16 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: BONFERRONI Bonferroni count: 3122 GO molecular function complete Homo sapiens - REFLIST (20580) upload_1 (129) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (P-value) N-acetyllactosamine synthase activity (GO:0003945) 5 5 .03 + > 100 2.79E-08 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity (GO:0008532) 5 5 .03 + > 100 2.79E-08 heparan sulfate sulfotransferase activity (GO:0034483) 15 15 .09 + > 100 1.22E-30 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity (GO:0050510) 4 4 .03 + > 100 4.60E-06 hyaluronan synthase activity (GO:0050501) 3 3 .02 + > 100 7.51E-04 chondroitin 4-sulfotransferase activity (GO:0047756) 4 4 .03 + > 100 4.60E-06 heparan sulfate 6-sulfotransferase activity (GO:0017095) 3 3 .02 + > 100 7.51E-04 heparan sulfate N-deacetylase activity (GO:0102140) 3 3 .02 + > 100 7.51E-04 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity (GO:0003831) 4 4 .03 + > 100 4.60E-06 N-acetylglucosamine deacetylase activity (GO:0050119) 3 3 .02 + > 100 7.51E-04 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase (GO:0047288) 3 3 .02 + > 100 7.51E-04 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (GO:0047238) 6 6 .04 + > 100 1.68E-10 [heparan sulfate]-glucosamine 3-sulfotransferase activity (GO:0008467) 7 7 .04 + > 100 1.01E-12 chondroitin sulfotransferase activity (GO:0034481) 7 7 .04 + > 100 1.01E-12 N-acetyllactosaminide alpha-2,3-sialyltransferase activity (GO:0008118) 3 3 .02 + > 100 7.51E-04 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity (GO:0015018) 3 3 .02 + > 100 7.51E-04 heparan sulfate N-sulfotransferase activity (GO:0015016) 4 4 .03 + > 100 4.60E-06 proteoglycan sulfotransferase activity (GO:0050698) 28 25 .18 + > 100 7.20E-50 N-acetylglucosamine 6-O-sulfotransferase activity (GO:0001517) 7 6 .04 + > 100 1.17E-09 dermatan sulfotransferase activity (GO:0120534) 6 5 .04 + > 100 1.67E-07 beta-galactosidase activity (GO:0004565) 5 4 .03 + > 100 2.29E-05 dermatan 4-sulfotransferase activity (GO:0001537) 5 4 .03 + > 100 2.29E-05 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity (GO:0003836) 7 5 .04 + > 100 5.81E-07 hyalurononglucosaminidase activity (GO:0004415) 8 5 .05 + 99.71 1.54E-06 galactosidase activity (GO:0015925) 7 4 .04 + 91.16 1.59E-04 sulfotransferase activity (GO:0008146) 53 29 .33 + 87.29 9.60E-48 hexosaminidase activity (GO:0015929) 15 8 .09 + 85.09 3.70E-11 hyaluronic acid binding (GO:0005540) 24 10 .15 + 66.47 3.73E-13 transferase activity, transferring sulphur-containing groups (GO:0016782) 70 29 .44 + 66.09 4.61E-43 UDP-galactosyltransferase activity (GO:0035250) 29 12 .18 + 66.01 3.23E-16 extracellular matrix structural constituent conferring compression resistance (GO:0030021) 22 9 .14 + 65.26 1.63E-11 3'-phosphoadenosine 5'-phosphosulfate binding (GO:0050656) 10 4 .06 + 63.81 9.38E-04 galactosyltransferase activity (GO:0008378) 31 12 .19 + 61.76 8.68E-16 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity (GO:0008499) 12 4 .08 + 53.18 2.19E-03 glucuronosyltransferase activity (GO:0015020) 34 11 .21 + 51.61 3.00E-13 sulfuric ester hydrolase activity (GO:0008484) 17 5 .11 + 46.92 1.63E-04 beta-1,3-galactosyltransferase activity (GO:0048531) 14 4 .09 + 45.58 4.39E-03 sialyltransferase activity (GO:0008373) 21 5 .13 + 37.98 5.25E-04 UDP-glycosyltransferase activity (GO:0008194) 146 31 .92 + 33.87 9.27E-36 acetylglucosaminyltransferase activity (GO:0008375) 44 9 .28 + 32.63 2.07E-08 acetylgalactosaminyltransferase activity (GO:0008376) 34 6 .21 + 28.15 1.96E-04 hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553) 91 16 .57 + 28.05 1.19E-15 hexosyltransferase activity (GO:0016758) 197 29 1.23 + 23.48 2.79E-28 glycosyltransferase activity (GO:0016757) 267 36 1.67 + 21.51 1.33E-34 hydrolase activity, acting on glycosyl bonds (GO:0016798) 130 16 .81 + 19.64 4.55E-13 glycosaminoglycan binding (GO:0005539) 241 15 1.51 + 9.93 9.86E-08 extracellular matrix structural constituent (GO:0005201) 168 10 1.05 + 9.50 3.35E-04 transferase activity (GO:0016740) 2263 68 14.18 + 4.79 3.53E-28 catalytic activity (GO:0003824) 5658 92 35.47 + 2.59 1.26E-21 Unclassified (UNCLASSIFIED) 2291 2 14.36 - .14 0.00E00 nucleic acid binding (GO:0003676) 3988 1 25.00 - .04 1.75E-07